Who do you think will win the Jaguar vs Colts game:?

My dad in fantasy draft I help him with picks and all. He has Peyton Manning (but also has Phillip River) and Dallas Clark, but we were considering Terry Holt of the Jags. Who do you think is going to win? Specific player that is going to get big yards, touchdowns, etc? Give me a reason not just "Peyton Manning is going to destroy them!!!" or "Maurice Jones-Drew is kick ***."